How Does the IVF Treatment Process Begin?
The IVF treatment process begins with a detailed preliminary evaluation by a specialist doctor. During the first examination, the couple’s medical history, previous treatment attempts, and general health status are reviewed. While the female patient is asked for examinations such as hormone tests, ultrasonography, and a hysterosalpingography (HSG), a sperm analysis is performed on the male patient. The data obtained at this stage helps determine the most suitable treatment protocol for the couple. This initial phase forms the foundation of the treatment plan and plays a critical role in achieving success.
What is Done During the First Examination and Evaluation Phase?
The first examination is conducted to obtain a comprehensive picture of the couple’s reproductive health. Blood tests are performed to determine the female patient’s ovarian reserve by checking hormone levels (such as AMH, FSH, and E2). Ultrasonography is used to evaluate the condition of the uterus and ovaries. If not done before, HSG is used to check the patency of the fallopian tubes and the structure of the uterine cavity. For the male patient, a sperm analysis is requested to examine sperm count, motility, and morphology. With Cure Holiday, this initial evaluation process is organized quickly and efficiently.
Which Tests are Mandatory for Treatment?
Before starting IVF treatment, certain mandatory tests are required for both the male and female. The female patient is asked for blood tests showing hormone levels (FSH, LH, E2, Prolactin, TSH), a complete blood count, blood type, and infectious disease screenings (Hepatitis B, C, HIV, VDRL). The male patient undergoes sperm analysis and infectious disease tests. Additionally, official documents proving that the couple is married are also legally mandatory. Cure Holiday makes the process easier by providing you with information about all the necessary documents and tests in advance.
How Does the Ovarian Stimulation Phase Work?
The ovarian stimulation phase is the process of stimulating the woman’s ovaries with the help of medications to obtain a large number of eggs. This stage usually begins on the 2nd or 3rd day of the menstrual cycle and lasts for about 10-12 days. The size and number of the eggs are regularly monitored with ultrasound and blood tests. When the eggs are determined to have reached the desired maturity, a trigger shot is administered, and the patient becomes ready for the egg retrieval procedure.
How is the Egg Retrieval (OPU) Procedure Performed?
Egg retrieval (OPU – Oocyte Pick-Up) is a painless procedure performed under light sedation, approximately 34-36 hours after the trigger shot. The specialist doctor uses a fine needle under vaginal ultrasound guidance to collect mature eggs from the follicles in the ovaries. This procedure takes an average of 15-20 minutes. Patients are discharged after resting for a few hours. This operation is the first and most important step in embryo formation.
How is the Sperm Collection Process Carried Out?
The sperm collection process is carried out on the same day as the egg retrieval. The male patient is asked to provide a sperm sample by masturbation in a private room. If sperm cannot be obtained by this method or if the sperm count is insufficient, surgical methods (such as TESE, TESA) can be applied. The collected sperm sample undergoes a special process in the laboratory to select the highest quality sperm.
How is Fertilization Done in the Laboratory?
Fertilization is the process of bringing the collected eggs and sperm together in a laboratory setting. Two main methods are used: conventional IVF and microinjection (ICSI). In the conventional method, the eggs and sperm are placed in the same dish, and the sperm are expected to fertilize the egg naturally. In the microinjection method, the healthiest sperm selected under a microscope is directly injected into each egg. This method offers high success rates, especially in cases of male infertility.
When and How is Embryo Transfer Performed?
Embryo transfer is the process of placing embryos that have completed 3 to 5 days of development in the laboratory into the expectant mother’s uterus with the help of a special catheter. The transfer is usually done at the 3rd day (cleavage) or 5th day (blastocyst) stage of the embryos. Blastocyst transfer is frequently preferred in modern IVF centers as it offers higher pregnancy rates. The procedure does not require anesthesia and the patient completes it comfortably.
What Should Be Done After Embryo Transfer?
Rest is very important after embryo transfer. Generally, bed rest is recommended for half an hour to an hour. Heavy exercises and physical activities should be avoided during this period. Medication treatment should be continued regularly, and the doctor’s recommendations should be followed meticulously. Activities such as sexual intercourse and heavy lifting should also be avoided. Drinking plenty of water and eating healthy also helps increase the chance of embryo implantation.
What Methods Are Used in Case of Recurrent IVF Failures?
Recurrent IVF failures are a complex situation that requires special examination. In these cases, the PGT (Preimplantation Genetic Diagnosis) method is used to examine the genetic structure of the embryos, and those without chromosomal abnormalities are selected. Additionally, methods such as hysteroscopy to detect intrauterine problems, immunological treatments for intrauterine immune system issues, or embryo glue can also be used. Cure Holiday aims to increase the chance of success by offering the latest technological approaches in such situations.
What Factors Affect the Success Rate of IVF Treatment?
Many factors affect the success rate of IVF treatment. The most important factors include the woman’s age, ovarian reserve and quality, sperm quality, and previous treatment history. In addition, uterine structure, embryo quality, and the treatment protocol used also directly affect success. As age advances, the quality of eggs decreases, so the success rate also decreases. Therefore, starting treatment at an early age is of great importance.
What Medications are Used During Treatment?
The medications used during IVF treatment are vital for supporting egg development and keeping the treatment process under control. The most commonly used medications include gonadotropins (hormones that stimulate egg development), GnRH antagonists or agonists (that prevent premature ovulation), and hCG (trigger shot). After treatment, supportive hormones like progesterone are used for the continuation of the pregnancy.
Are There Side Effects of Egg Development Medications?
The side effects of egg development medications vary from person to person but are generally mild. The most common side effects include slight abdominal bloating, tenderness, headache, fatigue, and slight redness at the injection site. Rarely, Ovarian Hyperstimulation Syndrome (OHSS) may develop, but this condition can be easily managed with modern protocols. Cure Holiday‘s expert team provides information about possible side effects and ensures your follow-up throughout the process.

What is the ICSI (Microinjection) Method in IVF Treatment?
ICSI (Intracytoplasmic Sperm Injection) is a fertilization method where a single sperm is directly injected into an egg. This method provides a great advantage, especially in cases of male infertility (low sperm count, motility, or morphology). It can also be preferred in cases where fertilization failure occurred in previous IVF attempts or when frozen eggs are used. This is one of the most important success-enhancing methods of IVF treatment.
When is PGT (Preimplantation Genetic Diagnosis) Used?
PGT is the process of genetically examining the embryo before it is transferred to the uterus. This method is used, especially in cases of advanced maternal age, recurrent miscarriages, recurrent IVF failures, or when one of the couple is a known carrier of a genetic disease. PGT helps detect abnormalities in chromosome number and structure, ensuring the transfer of healthy embryos. This significantly increases the chance of pregnancy.
How Long Does the Entire IVF Treatment Last?
The IVF treatment process varies depending on the patient’s treatment protocol and individual situation. Generally, the ovarian stimulation phase takes 10-12 days, egg retrieval takes 1 day, embryo culture takes 3-5 days, and embryo transfer takes 1 day. In total, the process from the start of treatment to the transfer stage can take approximately 15 to 20 days. This duration covers the entire process for patients coming from abroad and makes planning easier.
What is the Importance of Psychological Support in IVF Treatment?
IVF treatment can be a challenging process both physically and psychologically. Therefore, receiving psychological support throughout the treatment is extremely important. Feelings of stress, anxiety, and hopelessness can negatively affect the success of the treatment. Consultations with a specialist psychologist help couples manage this process more healthily, maintain emotional balance, and keep their motivation high. Cure Holiday offers this service as part of its packages to provide full support to its patients.
How Does the Process Work for Patients Coming from Abroad?
For patients coming from abroad, the IVF process begins with an online preliminary consultation. The patient’s documents are reviewed, and a personalized treatment plan is created. The ovarian stimulation phase can be started in the patient’s home country. However, they need to travel to Turkey for the egg retrieval and embryo transfer procedures. Cure Holiday organizes this entire process from start to finish, including airport transfers, accommodation, and interpreter services, to ensure maximum patient comfort.
Is Pain Felt During IVF Treatment?
IVF treatment is generally a painless process. Injections during the ovarian stimulation phase do not cause severe pain due to the very thin needles; they may only cause a slight feeling of discomfort. The egg retrieval procedure (OPU) is performed under light anesthesia (sedation), so the patient does not feel any pain. Embryo transfer is also a completely painless procedure and does not require anesthesia.
What is the Embryo Freezing Process and Why is it Important?
Embryo freezing (cryopreservation) is the process of freezing excess healthy embryos obtained during IVF treatment that are not transferred, using a special technique for future use. This method allows the treatment to continue without the need for a new egg retrieval and fertilization procedure if the patient’s first attempt is unsuccessful or if they wish to have a second child in the future. The legal storage period is 5 years.
What is the Legal Duration for Embryo Freezing and Storage?
According to Turkish law, embryos can be frozen and stored for a maximum period of five years. At the end of this period, the embryo storage period can be extended for another five years with the couple’s request and the permission of the Ministry of Health. This legal regulation provides security for the couple’s future pregnancy attempts while also aiming to protect legal and ethical standards.
Is IVF a Solution for Recurrent Miscarriages?
Yes, IVF treatment can be a solution for couples experiencing recurrent miscarriages. The underlying causes of recurrent miscarriages can include embryo chromosomal abnormalities, uterine anomalies, or immune system issues. In these cases, methods such as PGT (Preimplantation Genetic Diagnosis) to select genetically healthy embryos and hysteroscopy for intrauterine problems can help reduce the risk of miscarriage.
What IVF Methods Are Used for Male Infertility?
The most commonly used method for male infertility is ICSI (microinjection). In cases with severe sperm problems, sperm are retrieved directly from the testicles using surgical methods (TESE, TESA, micro-TESE). These methods increase the hope of having a child even for men who do not have sperm in their semen. Cure Holiday‘s partner clinics successfully apply the latest technological approaches in cases of male infertility.
Can I Travel During Treatment?
Traveling by plane during IVF treatment is generally safe, but it is recommended to rest for a few days after the embryo transfer. Long-term travels are not highly recommended for the first few days after the transfer as they can be stressful. Health tourism organizations like Cure Holiday provide a safe and comfortable travel experience by planning the patients’ trips according to their treatment schedule.
Is Gender Selection Legal in IVF Treatment?
Gender selection through IVF treatment in Turkey is legally prohibited unless there is a medical necessity, such as a genetic disease being passed down based on gender. This applies to all IVF centers that must comply with legal and ethical rules. Treatments are only focused on resolving infertility issues and achieving a healthy pregnancy.
What Should Be Considered Before Starting Treatment?
One of the most important things to consider before starting treatment is to stay away from harmful habits like smoking and alcohol. Eating a healthy and balanced diet, exercising regularly, and reaching an ideal body weight increase the chances of success. It is also important to stay away from stress and pay attention to sleep patterns. Cure Holiday offers special lifestyle and nutrition recommendations to you during this process.
How Should the Lifestyle Be After IVF Treatment?
After IVF treatment, a healthy lifestyle should be adopted for a healthy continuation of the pregnancy. It is important to use the medications your doctor recommends regularly, stay away from stress, avoid heavy physical activities, and eat healthily. Your pregnancy will be followed up like a normal pregnancy. Staying positive and taking good care of yourself is the most important step in this process.
How Does Cure Holiday Provide Support in This Process?
Cure Holiday offers comprehensive support to make the IVF treatment process easier for you. A personal patient coordinator is assigned to you from the first day. This coordinator is with you at every stage, from airport transfers to accommodation, from arranging your appointments to interpreter services. Additionally, they also guarantee your post-treatment follow-up with online counseling services when you return to your country.
When is the Pregnancy Test Done After Treatment?
In IVF treatment, the pregnancy test is done 10 to 12 days after the embryo transfer. This test is determined by a blood Beta-hCG test. It is important to be patient during this period and not to take the test prematurely, as early tests can give incorrect results. If a positive result is obtained, a new appointment with your doctor is arranged for the advanced stages of the pregnancy.
What Does the Cost of IVF Treatment Depend On?
The cost of IVF treatment depends on the methods used, the dosage and duration of medications, additional laboratory procedures (like PGT, ICSI), and extra services like embryo freezing. The quality of the clinic and its success rates also play a role in pricing. However, Cure Holiday‘s all-inclusive packages prevent unexpected costs and make the process more transparent.